I recently hit the 200k mile mark with my 11 F350 DRW 4x4 6.7
I ran it stock until around 95k, then i added a Spartan
tuner, DPF delete and Air box.
The only thing that has needed to be replaced is the Amp for the radio. Other than that, i had some shifting issues for a little time, but those have gone away.
Most of the trans shifting issues where during cold weather, it would stick between 2-3.
I have to say this has been the best vehicle i have owned. I was hauling travel trailers for a while so about 40% of these miles are towing. Now I just drive it around town and occasionally I carry my truck camper around.
Unloaded milage is around 16.5 city, and 18 why with the 50hp tune.
All in all i love the truck and its been great to me.